Dengue viruses are transmitted mainly by vector insects such as Aedes ae-gypti and Aedesalbopictus, causing dengue fever (DF) and their high morbidity and mortality from dengue hemorrhagic fever (DHF) and Dengue shock Syndrome (DSS).Patients and latent infections are the main source of infection, and primates in the jungle are the animal hosts that maintain the circulation of the virus in nature.Blood from febrile patients inoculated into the brains of immature mice could be isolated and immobilized.
Unlike other infectious diseases, dengue cannot be transmitted directly from one infected person to another. Instead, it spreads widely in a mosquito called Aedes aegypti.After World War II, widespread migration and urbanization in the Asia-Pacific region gave aedes aegypti mosquitoes a good place to live, and they were also able to fly across oceans in airplanes, causing a regional epidemic of dengue fever.In addition to Aedes aegypti, another close relative, Aedes albopictus, is an important contributor to the spread of dengue fever.[1]
These diseases are widely prevalent in tropical and subtropical areas, and are widely distributed, frequently occurring and harmful human infectious diseases.Serious threats have been posed in many countries in Asia, the Pacific Islands and in central and South America.It was also popular in Japan after World War II.Since then, the incidence of dengue virus infection has increased significantly in tropical and subtropical areas of Asia, Africa and South America.